Vitamin B6

Vitamin B6 (pyridoxine) can be found in certain foods such as cereals, beans, vegetables, liver, meat, and eggs. It can also be made in a laboratory. Pyridoxine is used for preventing and treating low levels of pyridoxine (pyridoxine deficiency) and the “tired blood” (anemia) that may result.[1][2] It is also used for heart disease; high cholesterol; reducing blood levels of homocysteine, a chemical that might be linked to heart disease; and helping clogged arteries stay open after a balloon procedure to unblock them (angioplasty).[1][2][4]

Women use pyridoxine for premenstrual syndrome (PMS) and other menstruation problems, "morning sickness" (nausea and vomiting) in early pregnancy, stopping milk flow after childbirth, depression related to pregnancy or using birth control pills, and symptoms of menopause.[5]

Pyridoxine is also used for Alzheimer's disease, attention deficit-hyperactivity disorder (ADHD), Down syndrome, autism, diabetes and related nerve pain, sickle cell anemia, migraine headaches, asthma, carpal tunnel syndrome, night leg cramps, muscle cramps, arthritis, allergies, acne and various other skin conditions, and infertility. It is also used for dizziness, motion sickness, preventing the eye disease age-related macular degeneration (AMD), seizures, convulsions due to fever, and movement disorders (tardive dyskinesia, hyperkinesis, chorea), as well as for increasing appetite and helping people remember dreams.[1][2][3][4][5][6][7][8][9]

Some people use pyridoxine for boosting the immune system, eye infections, bladder infections, and preventing cancer and kidney stones.[9] Pyridoxine is also used to overcome certain harmful side effects related to radiation treatment and treatment with medications such as mitomycin, procarbazine, cycloserine, fluorouracil, hydrazine, isoniazid, penicillamine, and vincristine. Pyridoxine is frequently used in combination with other B vitamins in vitamin B complex products (such as vitamin B12).

Vitamin B12

Vitamin B12 is a water-soluble vitamin that keeps your nerves and red blood cells healthy. It is responsible for the smooth functioning of several critical body processes. A deficiency in vitamin B12 can result in a host of illnesses like anemia, fatigue, weakness, constipation, loss of appetite, weight loss, depression, poor memory, soreness of the mouth, asthma, vision problems, and a low sperm count.[10][11][12][13]

The top 5 health benefits of vitamin B 12 are:

• It is needed to convert carbohydrates into glucose in the body, thus leading to energy production and a decrease in fatigue and lethargy in the body.
• It helps in healthy regulation of the nervous system, reducing depression, stress, and brain shrinkage.
• It helps maintain a healthy digestive system. Vitamin B12 also protects against heart disease by curbing and improving unhealthy cholesterol levels, protecting against stroke, and high blood pressure.
• It is essential for healthy skin, hair, and nails. It helps in cell reproduction and constant renewal of the skin.
• Vitamin B 12 helps protect against cancers including breast, colon, lung, and prostate cancer.

Getting enough B12 allows your body to make heme, a chemical component of hemoglobin, the protein that transports oxygen in your blood. Your body must constantly generate heme to make functional red blood cells, and cobalamin promotes this heme production. Taking vitamin B12 helps ensure you can make enough healthy red blood cells to oxygenate your tissue. Vitamin B12 also maintains healthy myelin, a fatty substance that promote nerve function. Our high grade vitamin B12 may also help protect against nerve damage caused by myelin breakdown.[14]

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, or cure any disease. The information provided above comes in part from NewsMax.

References

1. Rimm, E. B., Willett, W. C., Hu, F. B., Sampson, L., Colditz, G. A., Manson, J. E., ... & Stampfer, M. J. (1998). Folate and vitamin B6 from diet and supplements in relation to risk of coronary heart disease among women. Jama, 279(5), 359-364.

2. Naurath, H. J., Joosten, E., Riezler, R., Stabler, S., Allen, R. H., & Lindenbaum, J. (1995). Effects of vitamin B12, folate, and vitamin B6 supplements in elderly people with normal serum vitamin concentrations. The Lancet, 346(8967), 85-89.

3. Robinson, K., Arheart, K., Refsum, H., Brattström, L., Boers, G., Ueland, P., ... & European COMAC Group. (1998). Low circulating folate and vitamin B6 concentrations risk factors for stroke, peripheral vascular disease, and coronary artery disease. Circulation, 97(5), 437-443.

4. Pfeiffer, S. I., Norton, J., Nelson, L., & Shott, S. (1995). Efficacy of vitamin B6 and magnesium in the treatment of autism: a methodology review and summary of outcomes. Journal of Autism and Developmental Disorders, 25(5), 481-493.

5. Malouf, R., & Grimley Evans, J. (2003). Vitamin B6 for cognition. Cochrane Database Syst Rev, 4.

6. Balk, E. M., Raman, G., Tatsioni, A., Chung, M., Lau, J., & Rosenberg, I. H. (2007). Vitamin B6, B12, and folic acid supplementation and cognitive function: a systematic review of randomized trials. Archives of Internal Medicine, 167(1), 21-30.

7. Morrow, L. E., & Grimsley, E. W. (1999). Long-term diuretic therapy in hypertensive patients: effects on serum homocysteine, vitamin B6, vitamin B12, and red blood cell folate concentrations. Southern medical journal, 92(9), 866-870.

8. Kleijnen, J., Ter Riet, G., & KNIPSCHILD, P. (1990). Vitamin B6 in the treatment of the premenstrual syndrome–a review. BJOG: An International Journal of Obstetrics & Gynaecology, 97(9), 847-852.

9. Zhang, S. M., Moore, S. C., Lin, J., Cook, N. R., Manson, J. E., Lee, I. M., & Buring, J. E. (2006). Folate, vitamin B6, multivitamin supplements, and colorectal cancer risk in women. American journal of epidemiology, 163(2), 108-115.

10. Naurath, H. J., Joosten, E., Riezler, R., Stabler, S., Allen, R. H., & Lindenbaum, J. (1995). Effects of vitamin B12, folate, and vitamin B6 supplements in elderly people with normal serum vitamin concentrations. The Lancet, 346(8967), 85-89.

11. Tiemeier, H., Van Tuijl, H. R., Hofman, A., Meijer, J., Kiliaan, A. J., & Breteler, M. M. (2014). Vitamin B12, folate, and homocysteine in depression: the Rotterdam Study. American Journal of Psychiatry.

12. Wang, H. X., Wahlin, Å., Basun, H., Fastbom, J., Winblad, B., & Fratiglioni, L. (2001). Vitamin B12 and folate in relation to the development of Alzheimer’s disease. Neurology, 56(9), 1188-1194.

13. Reynolds, E. (2006). Vitamin B12, folic acid, and the nervous system. The lancet neurology, 5(11), 949-960.

14. Fenech, M. (2001). The role of folic acid and Vitamin B12 in genomic stability of human cells. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 475(1), 57-67.